Palinthorn NagsuwanchartSiriruk NakornchaiSroisiri ThaweboonRudee SuraritMahidol University, Faculty of Dentistry2022-08-042022-08-042021-12-01Pediatric Dental Journal. Vol.31, No.3 (2021), 242-24718803997091723942-s2.0-85114135837https://repository.li.mahidol.ac.th/handle/20.500.14594/76772Objective: To investigate the effect of mogroside, palatinose, erythritol, and xylitol on the dental plaque pH of children and to compare the plaque pH change between caries-active and caries-free children caused by these sweeteners. Methods: Thirty-six children (mean age 6.2 ± 2.9-year-old), caries-active and caries-free, were included. After refraining from practicing oral hygiene, the accessible plaque was collected and equally divided for challenging with 6 different solutions: mogroside, palatinose, erythritol, xylitol, 10% sucrose, and deionized water. The pH of each solution was measured using a digital pH meter at 0, 5, 10, 15, 20, 25, and 30 min. Results: Mogroside, erythritol, xylitol, and water did not significantly lower the dental plaque pH, however, palatinose reduced dental plaque pH comparable to sucrose (p < 0.05). Comparing the caries-active and caries-free groups, only sucrose produced significantly different pH value at min 5 and 10. Conclusions: Mogroside, erythritol, and xylitol did not lower the dental plaque pH in caries-active or caries-free children. However, palatinose affected the dental plaque pH similar to sucrose.Mahidol UniversityDentistryMedicineMogroside, palatinose, erythritol, and xylitol differentially affect dental plaque pH in caries-active and caries-free children: An in vitro studyArticleSCOPUS10.1016/j.pdj.2021.08.004