Samran PrabpaiSuthep WiyakruttaNongluksna SriubolmasPalangpon KongsaereeMahidol UniversityChulalongkorn University2018-11-232018-11-232015-10-01Phytochemistry Letters. Vol.13, (2015), 375-37818767486187439002-s2.0-84939192827https://repository.li.mahidol.ac.th/handle/20.500.14594/35087© 2015 Elsevier Ltd. Abstract Two new dihydronaphthalenones (1, 2) with four known compounds (3-6) were isolated as secondary metabolites of the endophytic fungus Nodulisporium sp. from Antidesma ghaesembilla. Their chemical structures were established based on 1D and 2D NMR spectroscopic data and HR-ESI-MS analyses. The relative configuration of 2 was confirmed by single crystal X-ray crystallographic analysis. A new isofuranonaphthalenone 2 displayed antimycobacterial and antimalarial activities with IC<inf>50</inf> values of 3.125 and 11.3 μg/mL, respectively.Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/j.phytol.2015.08.001