László SeperRichárd SchwabSirichai KiattavorncharoenAndre BüchterÁgnes BánkfalviUlrich JoosJózsef PiffkóBirgit Kruse-LoeslerWestfalische Wilhelms-Universitat MunsterSemmelweis EgyetemMahidol UniversityGroup Practice EngelkeGerhard-Domagk-Institut fur PathologieUniversitat Duisburg-Essen2018-08-242018-08-242007-12-01Head and Face Medicine. Vol.3, No.1 (2007)1746160X2-s2.0-38749149588https://repository.li.mahidol.ac.th/handle/20.500.14594/24407Background. Soft tissue sarcomas in the head and neck region are rare and often present a difficult differential diagnosis. The aim of our presentation is to point out the complexity of the diagnosis, treatment and follow up. Case presentation. An eighty-seven year old female patient was referred to our unit with a fast growing brownish lump on the face. Four months beforehand, a benign fibrous histiocytoma (BFH) had been removed from the same location by excision biopsy with wide tumour-free resection margins. Excision biopsy of the recurrent lesion revealed a malignant fibrous histiocytoma (MFH). Radical tumour resection was completed by extended parotidectomy and neck dissection; the skin defect was covered by a regional bi-lobed flap. No adjuvant radio- or chemotherapy was administered. Full functional and cosmetic recovery was achieved; follow-up has been uneventful more than two years postoperatively. Discussion. Malignant transformation of BFH is extremely rare and if so, extended radical surgery may give a fair chance for a favourable outcome even in patients with advanced age. © 2007 Seper et al; licensee BioMed Central Ltd.Mahidol UniversityDentistryMedicineArticleSCOPUS10.1186/1746-160X-3-36