Prevalence and sequence diversity of a factor required for actin-based motility in natural populations of Burkholderia species

Chayada SitthidetJoanne M. StevensNarisara ChantratitaBart J. CurrieSharon J. PeacockSunee KorbsrisateMark P. StevensMahidol UniversityThe Pirbright InstituteMenzies School of Health Research2018-07-122018-07-122008-07-01Journal of Clinical Microbiology. Vol.46, No.7 (2008), 2418-2422009511372-s2.0-49049112903https://repository.li.mahidol.ac.th/handle/20.500.14594/19622Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires BimA. We report a high degree of conservation of bimA in 99 B. pseudomallei isolates from the area of endemicity. A geographically restricted subset of B. pseudomallei isolates harbored a B. mallei-like bimA allele (12.1%), confounding a differential diagnostic test based on amplification of species-specific bimA regions. Copyright © 2008, American Society for Microbiology. All Rights Reserved.Mahidol UniversityMedicinePrevalence and sequence diversity of a factor required for actin-based motility in natural populations of Burkholderia speciesArticleSCOPUS10.1128/JCM.00368-08