W. J. FokkensV. J. LundC. HopkinsP. W. HellingsR. KernS. ReitsmaS. Toppila-SalmiM. Bernal-SprekelsenJ. MullolI. AlobidW. Terezinha Anselmo-LimaC. BachertF. BaroodyC. von BuchwaldA. CervinN. CohenJ. ConstantinidisL. De GaboryM. DesrosiersZ. DiamantR. G. DouglasP. H. GevaertA. HafnerR. J. HarveyG. F. JoosL. KalogjeraA. KnillJ. H. KocksB. N. LandisJ. LimpensS. LebeerO. LourencoC. MecoP. M. MatricardiL. O'MahonyC. M. PhilpottD. RyanR. SchlosserB. SeniorT. L. SmithT. TeelingP. V. TomazicD. Y. WangD. WangL. ZhangA. M. AgiusC. Ahlstrom-EmanuelssonR. AlabriS. AlbuS. AlhabashA. AleksicM. AloulahM. Al-QudahS. AlsalehM. A. BabanT. BaudoinT. BalversP. BattagliaJ. D. BedoyaA. BeuleK. M. BofaresI. BravermanE. Brozek-MadryB. RichardC. CallejasS. CarrieL. CaulleyD. ChussiE. de CorsoA. CosteU. El HadiA. ElfaroukP. H. EloyS. FarrokhiG. FelisatiM. D. FerrariR. FishchukW. GraysonP. M. GoncalvesB. GrdinicV. GrgicA. W. HamizanJ. V. HeinichenS. HusainT. I. PingJ. IvaskaF. JakimovskaL. JovancevicE. KakandeR. KamelS. KarpischenkoH. H. KariyawasamH. KawauchiA. KjeldsenL. KlimekA. KrzeskiG. Kopacheva BarsovaS. W. KimD. LalJ. J. LetortKlinički Bolnički Centar Sestre MilosrdniceCHU UCL NamurUniversity of East Anglia, Norwich Medical SchoolEdinburgh Medical SchoolHospital de ClínicasUniversity of Banja LukaSveučilište u Zagrebu, Farmaceutsko Biokemijski FakultetSkin and Allergy HospitalUniversity of SulaimaniyaFondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro CuoreBeijing Tongren Hospital, Capital Medical UniversityL-Università ta' MaltaSS Cyril and Methodius UniversityOmar Al-Mukhtar UniversitySultan Qaboos UniversityMakerere UniversityKilimanjaro Christian Medical CollegeMedical University of WarsawUniversity of Novi SadAmerican University of BeirutUniversity Hospital of GhentVilniaus universitetasUniversidad de AntioquiaJordan University of Science and TechnologyUniversiteit GentKU Leuven– University Hospital LeuvenThe University of QueenslandKøbenhavns UniversitetUniversità degli Studi di MilanoRoyal National Throat, Nose and Ear HospitalPontificia Universidad Católica de ChileLunds UniversitetUniversity of Ottawa, CanadaRoyal Brisbane and Women's HospitalStockholms universitetHille Yaffe Medical Center IsraelThe University of Alabama at BirminghamMayo Clinic Scottsdale-Phoenix, ArizonaYong Loo Lin School of MedicineShimane UniversityCharité – Universitätsmedizin BerlinUniversity College CorkUniversité Paris-Est CréteilUniversiti Malaysia SarawakMedical University of South CarolinaUniversity of Chicago Medicine Comer Children's HospitalUNC School of MedicineMacquarie UniversitySyddansk UniversitetOregon Health & Science UniversityCharles UniversityLeiden University Medical Center - LUMCBushehr University of Medical SciencesAristotle University of ThessalonikiParacelsus Medizinische PrivatuniversitatSkånes universitetssjukhusNorthwestern University Feinberg School of MedicineKing Saud UniversityUniversitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-NapocaUniversiteit AntwerpenAnkara ÜniversitesiCairo UniversityHôpitaux universitaires de GenèveFudan UniversityUniversity of MontrealUniversidade de Sao Paulo - USPUniversitätsklinikum MünsterUniversity of Zagreb School of MedicineMedizinische Universität GrazNewcastle University, United KingdomUniversity of AucklandGuy's and St Thomas' NHS Foundation TrustUniversità degli Studi dell'InsubriaUniversity of Pennsylvania Perelman School of MedicineGroupe Hospitalier PellegrinPavlov UniversityUniversity of ValenciaUniversiteit van AmsterdamKyung Hee UniversityUniversiti Kebangsaan MalaysiaUniversitat de BarcelonaJames Paget University Hospitals NHS Foundation TrustUniversidade da Beira InteriorDirector of Saint Petersburg Research Institute of Ear, Throat, Nose and SpeechENT DepartmentPersian Gulf Tropical Medicine Research CenterUniversity If MedicineResearch Director Respiratory and AllergyCentral city clinical hospital of lvano-Frankivsk city councilPontifical University Catholic of EcuadorCentro Hospitalar de Entre Douro e VougaPatient representativeZagreb University School of MedicineObservational and Pragmatic Research InstitutePatient RepresentativeCenter for Rhinology and AllergologyOptimum Patient CareMulago National Referral HospitalGeneral HospitalRoy. Nat. ENT Hosp.2020-08-252020-08-252020-02-20Rhinology. Vol.58, (2020), 1-464030007292-s2.0-85079830392https://repository.li.mahidol.ac.th/handle/123456789/58205The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was published and addresses areas not extensively covered in EPOS2012 such as paediatric CRS and sinus surgery. EPOS2020 also involves new stakeholders, including pharmacists and patients, and addresses new target users who have become more involved in the management and treatment of rhinosinusitis since the publication of the last EPOS document, including pharmacists, nurses, specialised care givers and indeed patients themselves, who employ increasing self-management of their condition using over the counter treatments. The document provides suggestions for future research in this area and offers updated guidance for definitions and outcome measurements in research in different settings. EPOS2020 contains chapters on definitions and classification where we have defined a large number of terms and indicated preferred terms. A new classification of CRS into primary and secondary CRS and further division into localized and diffuse disease, based on anatomic distribution is proposed. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, allergic rhinitis, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. All available evidence for the management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is systematically reviewed and integrated care pathways based on the evidence are proposed. Despite considerable increases in the amount of quality publications in recent years, a large number of practical clinical questions remain. It was agreed that the best way to address these was to conduct a Delphi exercise . The results have been integrated into the respective sections. Last but not least, advice for patients and pharmacists and a new list of research needs are included. The full document can be downloaded for free on the website of this journal: http://www.rhinologyjournal.com.Mahidol UniversityMedicineArticleSCOPUS10.4193/Rhin20.600