Bamboro S.A.Jabbar F.A.Bagita-Vangana M.Hasibuan N.Degaga T.S.Ghanchi N.Beg M.A.Tripura R.Pasaribu Pitaloka A.Tego T.T.Safitri W.YulitaCassidy-Seyoum S.Mwaura M.Mnjala H.Lee G.Dysoley L.Von Seidlein L.Price R.N.Unger H.W.Adhikari B.Thriemer K.Mahidol University2025-04-082025-04-082025-01-01Journal of Clinical and Translational Science (2025)https://repository.li.mahidol.ac.th/handle/123456789/109382Background. Researchers acknowledge the need to share study results with the patients and their communities, but this is not done consistently due to a plethora of barriers, including a paucity of data to guide best practice approaches in different populations. Methods. This study was nested within a large multi-centre randomized controlled trial of antimalaria treatment. Data on dissemination preferences were collected at the third month follow-up visit using a short questionnaire. Data were analysed using descriptive statistics and subsequently fed into an iterative process with key stakeholders, to develop suitable strategies for result dissemination. Results. A total of 960 patients were enrolled in the trial, of whom 84.0% participated in the nested survey. A total of 601 (74.6%) participants indicated interest in receiving trial results. There was significant heterogeneity by study country, with 33.3% (58/174) of patients indicating being interested in Cambodia, 100% (334/334) in Ethiopia, 97.7% (209/214) in Pakistan, but none (0/85) in Indonesia. The preferred method of dissemination varied by site, with community meetings favoured in Ethiopia (79.0%, 264/334) and individualised communication such as a letter (27.6%, 16/58) or phone calls (37.9%, 22/58) in Cambodia. Dissemination strategies were designed with key stakeholders and based on patient preferences but required adaptation to accommodate local logistical challenges. Conclusion. The varying preferences observed across different sites underscore that a onesize- fits-all approach is inadequate. Strategies can be tailored to patient preference but require adaptation to accommodate logistical challenges.MedicineArticleSCOPUS10.1017/cts.2025.562-s2.0-10500125138320598661