Anoma SantiworakulSuwannee JarungjitareeWattana JalayondejaSomchai ChantarothornSupoj SupaibulpipatMahidol University, Faculty of Physical Therapy and Applied Movement ScienceWalailak University, School of Allied Health Sciences and Public HealthSomdej Phrapinklao Hospital, Department of Pulmonary MedicineNopparatrajathanee Hospital, Department of Medicine2013-05-082018-03-232013-05-082018-03-232013-04-222009-04Journal of the Medical Association Thailand. Vol.92, No.4 (2009), 556-5630125-2208https://repository.li.mahidol.ac.th/handle/20.500.14594/10380Objective: Investigate the effect of lower extremity exercise on maximum lower extremity muscle strength and physical capacity in COPD patients. Material and Method: Twenty moderate to very severe COPD patients were allocated into trained and control groups. The trained group received eight weeks of lower extremity functional exercise including forward step up, lateral step up, heel raise, and lunge at home. Maximum muscle strength and Six Minute Walk Distance (6MWD) assessments were performed at pre-training, week 4, and week 8 in hospital settings. Results: There was no significant difference between trained and control groups in maximum muscle strength and 6MWD at the beginning of the program. However, there was a significant improvement in 6MWD after eight weeks of training, whereas there were no significant differences in the control group. Conclusion: Functional exercise may improve physical capacity in moderate to very severe COPD patients. It is beneficial and easy to perform at homeengMahidol UniversityExercise testExercise toleranceLower extremityMuscle strengthPulmonary diseaseChronic obstructiveWalkingArticleMedical Association of Thailand