Narong BunyaratavejKaiming ChanNarainswani SubramanianMahidol UniversityChinese University of Hong KongUniversity of Malaya2018-09-072018-09-072001-10-01Journal of the Medical Association of Thailand. Vol.84, No.SUPPL. 2 (2001)012522082-s2.0-0142139057https://repository.li.mahidol.ac.th/handle/123456789/26710Hyaluronic acid is a component of synovial fluid, in osteoarthritis (OA) and shows a change of property of hyaluronic acid especially its viscoelasticity causing degradation of the cartilage. Injection of hyaluronic acid into OA of the knee (Hyalgan® 2 ml/wk for 4 doses) in international multicentres gave dramatic responses : decreased pain, increased mobility of the joint after 49 days of injections compared to a placebo (2 ml of normal saline) p<0.01.Mahidol UniversityMedicineArticleSCOPUS