Constituents of the leaves and twigs of Ficus hispida

Sergio R. Peraza-SánchezHee Byung ChaiGeun Shin YoungThawatchai SantisukVichai ReutrakulNorman R. FarnsworthGeoffrey A. CordellJohn M. PezzutoA. Douglas KinghornUniversity of Illinois at ChicagoThe Forest Herbarium, Thailand Ministry of Natural Resources and EnvironmentMahidol University2018-07-242018-07-242002-03-05Planta Medica. Vol.68, No.2 (2002), 186-188003209432-s2.0-0036183143https://repository.li.mahidol.ac.th/handle/123456789/19989A new norisoprenoid, ficustriol (1), and the known phenanthroindolizidine alkaloid O-methyltylophorinidine (2), were isolated from a CHCI3 extract of the leaves and twigs of Ficus hispida. O-Methyltylophorinidine showed potent cytotoxic activity when tested against a small panel of human cancer cells, while ficustriol was inactive. The structure and stereochemistry of 1 were determined using chemical and spectral methods.Mahidol UniversityAgricultural and Biological SciencesChemistryPharmacology, Toxicology and PharmaceuticsConstituents of the leaves and twigs of Ficus hispidaArticleSCOPUS10.1055/s-2002-20257