Kesinee ChotivanichJuntima SritabalRachanee UdomsangpetchPaul NewtonKatarzyna A. StepniewskaRonatrai RuangveerayuthSornchai LooareesuwanDavid J. RobertsNicholas J. WhiteMahidol UniversityMae Sot General HospitalJohn Radcliffe Hospital2018-07-242018-07-242004-03-15Journal of Infectious Diseases. Vol.189, No.6 (2004), 1052-1055002218992-s2.0-1642328392https://repository.li.mahidol.ac.th/handle/20.500.14594/21688The relationship of the platelet-mediated autoagglutination of Plasmodium fakiparum-infected red blood cells (IRBCs) to disease severity was investigated in 182 Thai patients with falciparum malaria; it was evident in 43% of uncomplicated malaria (n = 63), 41% of severe malaria (n = 104), and 100% of cerebral malaria (n = 15; P = .001) isolates. The median (range) number of IRBCs in agglutinates per 1000 IRBCs was significantly higher in cerebral malaria (6 [3-42]) than in severe (0 [0-52]) and uncomplicated (0 [0-24]) malaria (P = .01). In multivariate analyses, high parasitemia and cerebral malaria were associated independently with parasite agglutination.Mahidol UniversityMedicineArticleSCOPUS10.1086/381900