Wichana ChamroonratFaculty of Medicine, Ramathibodi Hospital, Mahidol University2020-08-252020-08-252020-07-01PET Clinics. Vol.15, No.3 (2020), 361-36918799809155685982-s2.0-85085556486https://repository.li.mahidol.ac.th/handle/20.500.14594/58088© 2020 Elsevier Inc. Fever in children is common. If it persists and its cause cannot be identified in a reasonable time, along with laboratory and conventional imaging investigations, it is defined as fever of unknown origin (FUO). 18F-fluorodeoxyglucose (FDG) PET/computed tomography (CT) is well established in the evaluation of malignancy, which is a possible cause of FUO. FDG often locates inflammatory and infectious lesions considered nonspecific or false-positive for oncology; however, these findings are beneficial in FUO evaluation because infectious and inflammatory diseases are important FUO causes. FDG-PET/CT is being increasingly used for investigation of FUO as well as infectious/inflammatory disease.Mahidol UniversityMedicinePhysics and AstronomyReviewSCOPUS10.1016/j.cpet.2020.03.002