Narayanan ParthasarathyDavid DeShazerSharon J. PeacockVanaporn WuthiekanunMarilyn J. EnglandSarah L. NorrisDavid M. WaagU.S. Army Medical Research Institute of Infectious DiseasesMahidol University2018-07-122018-07-122008-01-01Journal of Carbohydrate Chemistry. Vol.27, No.1 (2008), 32-4015322327073283032-s2.0-45949089731https://repository.li.mahidol.ac.th/handle/20.500.14594/18998Burkholderia pseudomallei is the causative agent of melioidosis, a bacterial infection endemic in tropical regions including southeast Asia and northern Australia. B. pseudomallei contains structurally unique polysaccharides (capsular polysaccharide and O-antigen saccharides of lipopolysaccharide). A polysaccharide microarray platform was developed by immobilizing these polysaccharides onto glass slides. Employing this microarray, we were able to demonstrate the presence of antibodies to these polysaccharide antigens in the sera of melioidosis patients, but not in serum from nonmelioidosis human subjects. The advantages of this polysaccharide microarray technology over the conventional tests for the serodiagnosis of melioidosis are discussed. Copyright © Taylor & Francis Group, LLC.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1080/07328300802030761