Amar NawatheVignendra AriyarajahSirin ApiyasawatIvan BaracDavid H. SpodickClara Maass Medical CenterBrooklyn Hospital CenterMahidol UniversityUniversity of ManitobaSaint Vincent Hospital Worcester2018-10-192018-10-192013-08-01American Journal of Cardiology. Vol.112, No.3 (2013), 416-41918791913000291492-s2.0-84880339166https://repository.li.mahidol.ac.th/handle/123456789/32242Left atrial (LA) abnormality, an easily quantifiable parameter of left ventricular (LV) diastolic dysfunction, has been associated with cardiovascular risk similar to that of LV hypertrophy. The correlation between LV hypertrophy and LA abnormality among patients undergoing myocardial perfusion (MP) study has not been described. We prospectively studied 78 consecutive patients with LV hypertrophy who underwent MP study after screening for electrocardiographic and echocardiographic LA abnormality over a 6-month period. Of those, 48 had a positive MP imaging result, and 30 did not. LA size (p = 0.002) and P-wave duration (p = 0.017) were significantly increased in the former. The differential change in LA size (no defect = 35 ± 4, mild = 36 ± 5, moderate = 38 ± 5, severe = 44 ± 5 mm; p <0.0001) and P-wave duration (no defect = 107 ± 14, mild = 110 ± 17, moderate = 113 ± 15, severe = 127 ± 22 ms; p = 0.003) was greatest when the MP study defect exceeded moderate severity. In conclusion, the presence of LA abnormality could assist during MP study interpretation among patients with LV hypertrophy when such markers appear to be correlated with the severity of the MP study defect. © 2013 Elsevier Inc. All rights reserved.Mahidol UniversityMedicineArticleSCOPUS10.1016/j.amjcard.2013.03.047