Jongkonporn PhetcharawetchNolan M. BetterleyVichai ReutrakulDarunee SoorukramPawaret LeowanawatChutima KuhakarnMahidol University2022-08-042022-08-042021-10-01Journal of Fluorine Chemistry. Vol.250, (2021)002211392-s2.0-85114303231https://repository.li.mahidol.ac.th/handle/123456789/76013Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety of 3-((trifluoromethyl)thio)indoles in moderate to good yields within one step, open-air, and short reaction time.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryEnvironmental ScienceSynthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf>ArticleSCOPUS10.1016/j.jfluchem.2021.109878