Pakpoom PhoompoungMethee ChayakulkeereePopchai NgamskulrungrojAnanya PongpaibulFaculty of Medicine, Siriraj Hospital, Mahidol University2020-01-272020-01-272019-02-15Mycopathologia. Vol.184, No.1 (2019), 177-180157308320301486X2-s2.0-85061268163https://repository.li.mahidol.ac.th/handle/123456789/49811© 2018, Springer Science+Business Media B.V., part of Springer Nature. Histoplasma capsulatum is one of the most common pathogenic dimorphic fungi in Thailand. Its usual clinical syndrome is progressive disseminated histoplasmosis, whereas isolated hepatic histoplasmosis is extremely rare. Here, we report the world’s first reported case of hepatic histoplasmosis with pylephlebitis in a 45-year-old Thai male who underwent orthotopic liver transplantation due to hepatitis B cirrhosis. Histopathology of the recipient’s liver showed infiltration of fungal organisms in portal vein and hepatic granulomas. Serum H. capsulatum antibody was positive, and molecular identification from the liver revealed the DNA of H. capsulatum.Mahidol UniversityAgricultural and Biological SciencesImmunology and MicrobiologyReviewSCOPUS10.1007/s11046-018-0265-6