Iodine-catalyzed oxidative cross-coupling of indoles and azoles: Regioselective synthesis of N -linked 2-(Azol-1-yl)indole derivatives

Danupat BeukeawKwanchanok UdomsaspornSirilata YotphanMahidol University2018-11-232018-11-232015-04-03Journal of Organic Chemistry. Vol.80, No.7 (2015), 3447-345415206904002232632-s2.0-84926442873https://repository.li.mahidol.ac.th/handle/20.500.14594/35753© 2015 American Chemical Society. A highly efficient iodine-catalyzed regioselective oxidative cross-coupling of an indole C-H bond and azole N-H bond is described. This metal-free reaction can be easily carried out at room temperature under mild and environmentally friendly conditions and provides a series of N-linked 2-(azol-1-yl)indole derivatives in moderate to excellence yields.Mahidol UniversityChemistryIodine-catalyzed oxidative cross-coupling of indoles and azoles: Regioselective synthesis of N -linked 2-(Azol-1-yl)indole derivativesArticleSCOPUS10.1021/jo502933e