Stuart D. BlacksellLee SmytheRattanaphone PhetsouvanhMichael DohntRudy HartskeerlMeegan SymondsAndrew SlackManivanh VongsouvathViengmone DavongOlay LattanaSimmaly PhongmanyValy KeolouangkotNicholas J. WhiteNicholas P.J. DayPaul N. NewtonMahosot HospitalUniversity of OxfordMahidol UniversityWorld Health Organization, AustraliaRoyal Tropical Institute - KIT2018-08-202018-08-202006-10-01Clinical and Vaccine Immunology. Vol.13, No.10 (2006), 1166-1169155668112-s2.0-33750334679https://repository.li.mahidol.ac.th/handle/20.500.14594/22973The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admission serum (Leptotek sensitivity of 47.3% and specificity of 75.5%: ELISA sensitivity of 60.9% and specificity of 65.6%) compared to the Leptospira "gold standard" microscopic agglutination test. Copyright © 2006, American Society for Microbiology. All Rights Reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicineArticleSCOPUS10.1128/CVI.00219-06