Cheerasook ChongkolwatanaSiriporn LimviriyakulWorawong SlisatkornWarut PongsapichFaculty of Medicine, Siriraj Hospital, Mahidol University2019-08-282019-08-282018-06-01Journal of the Medical Association of Thailand. Vol.101, No.6 (2018), 859-862012522082-s2.0-85049131350https://repository.li.mahidol.ac.th/handle/123456789/46610© 2018, Medical Association of Thailand. All rights reserved. Background: Aggressive fibromatosis is rare in the neck and superior mediastinal area Case report: A 76-year-old woman initially presented with a large anterior neck mass with upper airway obstruction due to tracheal compression. Surgical excision was performed 3 years after the initial presentation, followed by post-operative radiation due to positive margin. No evidence of disease recurrence was observed during the 3-year follow up. Conclusion: Aggressive fibromatosis of head and neck is a challenging lesion due to its infiltrative nature, high propencity to recur and proximity to vital structures. Surgery should be well-planned using imaging and multidisciplinary approaches.Mahidol UniversityMedicineArticleSCOPUS