S. PhanichphantV. AtichartakarnP. NitiyanantV. TanphaichitrT. SupasitiMahidol University2018-10-122018-10-121982-09-10Clinical Nephrology. Vol.17, No.6 (1982), 319-322030104302-s2.0-0019967662https://repository.li.mahidol.ac.th/handle/20.500.14594/30388A 16 year-old male with severe metabolic acidosis required huge doses of sodium bicarbonate to alleviate his symptoms. Subsequent investigation showed that his bone marrow and kidneys were infiltrated with myelomonoblasts. His clinical course showed a temporal relationship between acute myelomonoblastic leukemia and metabolic acidosis. The literature on various etiologies of metabolic acidosis is reviewed. This is probably the first documented case of acute leukemia with the simultaneous occurrence of renal tubular, lactic and ketoacidoses.Mahidol UniversityMedicineArticleSCOPUS