Narong SarisutaJugpun SirithunyalugMahidol UniversityChiang Mai University2018-06-142018-06-141988-01-01Drug Development and Industrial Pharmacy. Vol.14, No.5 (1988), 683-687036390452-s2.0-0023906605https://repository.li.mahidol.ac.th/handle/20.500.14594/15525The purpose of this investigation was a study on sustained release coated granules manufactured by means of the air-suspension coating technique. The smoothed 12/20-mesh fractions of indomethacin granulation containing povidone as a binder were coated in a modified air-suspension coater with film of ethylcellulose-glyceryl monostea-rate mixture at various percents by weight of coat. The kinetics of drug release was determined and appears to conform to the first-order fashion. The relationship between the coating weight and the first-order release rate constant was developed and found to be in the form of exponential function. © 1988 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.3109/03639048809151893