Sirichai Kiattavorncharoenศิริชัย เกียรติถาวรเจริญChavengkiat Saengsirinavinเชวงเกียรติ แสงศิรินาวินNatthamet Wongsirichatณัฐเมศร์ วงศ์สิริฉัตรPing, BusharaIm, PuthavyDurward, CullumMahidol University. Faculty of Dentistry. Department of Oral and Maxillofacial Surgery2015-01-272017-01-052015-01-272017-01-052015-01-27Ping B, Kiattavorncharoen S, Saengsirinavin C, Im P, Wongsirichat N. Effect of high concentration lidocaine for mandibular teeth anesthesia: Review literature. M Dent J. 2014; 34(3): 364-72.0125-5614 (printed)https://repository.li.mahidol.ac.th/handle/20.500.14594/1066Inferior alveolar nerve block (IANB) is the most regularly used technique to anesthetize the mandibular teeth. Many authors have reported IAN block does not always result in completely success of pulpal anesthesia for the duration of the operation. The failure rates of pulpal anesthesia were reported from 10% to 39%. Many researches were manipulated several of ways to enhance the efficacy of local anesthetic use in dentistry. Many articles prove that high pH of local anesthetic enhances ionization property and provides sufficiency onset of local anesthetic. Furthermore, increasing concentration of lidocaine results in superior success rate compare to 2% lidocaine. To make a clear impression in effect of high concentration of lidocaine in mandibular anesthesia the further investigation should be encouraged. This review is to conclude ideas of related papers which studied in effect of increase concentration of lidocaine local anesthetic with vasoconstrictor in intraoral anesthesia.engMahidol UniversityEfficacyConcentrationInferior alveolar nerve blockLidocaine hydrochlorideMandibular teethHemodynamic changeOpen Access articleวิทยาสารทันตแพทยศาสตร์มหิดลMahidol Dental JournalArticleFaculty of Dentistry Mahidol University