Siripakorn SangkitpornBudsaba RerkamnuaychokeSomchai SangkitpornChartchai MitrakulYavamal SutivigitThailand Ministry of Public HealthSongkhla HospitalMahidol UniversityRegional Medical Sciences Center2018-07-242018-07-242002-05-01Journal of the Medical Association of Thailand. Vol.85, No.5 (2002), 577-582012522082-s2.0-0036562796https://repository.li.mahidol.ac.th/handle/20.500.14594/20501Hemoglobin G Makassar was identified in a family of Thai origin, which was found to share identical properties with hemoglobin S in routine hemoglobin separation both by cellulose acetate electrophoresis and cation-exchange HPLC. It is, therefore, subjects with hemoglobin G Makassar and hemoglobin S who may sometimes be mistakenly identified for each other. In this study, identification of hemoglobin G Makassar was achieved by DNA sequence analysis, which revealed a single nucleotide substitution GAG→GCG at codon 6 of the beta-globin gene. The hemoglobin variant was hemoglobin G Makassar [beta 6 : Glu→Ala]. This is the first report of hemoglobin G Makassar in Thailand.Mahidol UniversityMedicineArticleSCOPUS