T. RobertsD. LimmathurotsakulP. TurnerN. P.J. DayW. P. VandepitteB. S. CooperRangsit UniversityMahidol UniversityQueen Sirikit National Institute of Child HealthNuffield Department of Clinical MedicineMahosot HospitalAngkor Hospital for Children2020-01-272020-01-272019-10-01Journal of Hospital Infection. Vol.103, No.2 (2019), 151-15515322939019567012-s2.0-85065841212https://repository.li.mahidol.ac.th/handle/20.500.14594/51397© 2019 The Author(s) Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay.Mahidol UniversityMedicineArticleSCOPUS10.1016/j.jhin.2019.04.004