Panotpol TermsinsukTanyaporn ChantarojanasiriNonthalee PausawasdiFaculty of Medicine, Siriraj Hospital, Mahidol UniversityRajavithi Hospital2020-08-252020-08-252020-01-01Clinical Journal of Gastroenterology. (2020)18657265186572572-s2.0-85087628653https://repository.li.mahidol.ac.th/handle/20.500.14594/58279© 2020, Japanese Society of Gastroenterology. Afferent loop syndrome (ALS) is a mechanical complication that arises after gastric surgery with gastrojejunostomy reconstruction. This condition was first described in 1950 by Roux, Pedoussaut, and Marchal to post-gastrectomy patients with bilious vomiting. Acute ALS is associated with complete obstruction and considered a surgical emergency, whereas chronic ALS is mostly related to partial obstruction of the afferent loop. The delay in diagnosis may lead to intestinal ischemia, perforation and can be associated with a high mortality rate up to 60%. Surgery is usually the mainstay treatment of ALS, but endoscopic therapy, including stent placement in malignancy-related, anastomotic stricture dilation, has been evolving over the past recent years.Mahidol UniversityMedicineReviewSCOPUS10.1007/s12328-020-01170-z