Jariya ChuthapisithPasinee TaycharpipranaiRawiwan RoongpraiwanNichara RuangdaraganonMahidol UniversitySomdej Prapinklao Hospital2018-11-092018-11-092014-02-01Pediatrics International. Vol.56, No.1 (2014), 31-341442200X132880672-s2.0-84894502613https://repository.li.mahidol.ac.th/handle/20.500.14594/34302Background The Children's Communication Checklist (CCC) was developed to provide an assessment of domains of language impairment in children, particularly the pragmatic domain. This study examined the effectiveness of the CCC-Thai version in discriminating children with autism spectrum disorders (ASD) from typically developing children. Methods The parents of two groups of 50 children aged 4-6 years, one with clinically ascertained ASD, and one with typical development, completed the CCC-Thai version. Results The mean pragmatic composite score was significantly lower in the ASD group (124.6) than in the typical development group (142). The optimal receiver operating characteristic curve cut-off score was found to be identical to the original English version (132). Corresponding sensitivity and specificity were 94% and 86%, respectively. The positive predictive value and the negative predictive value were 87% and 93%, respectively. The corresponding area under the curve was 0.95 (95% confidence interval: 0.91-0.99). Conclusion The CCC-Thai version is a promising instrument to assess pragmatic language impairment in Thai children. © 2013 The Authors.Mahidol UniversityMedicineArticleSCOPUS10.1111/ped.12216