Nopporm ThasanaSomsak RuchirawatChulabhorn Research InstituteMahidol University2018-07-242018-07-242003-01-01Synlett. No.7 (2003), 1037-1039093652142-s2.0-0038538272https://repository.li.mahidol.ac.th/handle/20.500.14594/20824The application of directed remote metalation (DreM) and electrophilic substitution is reported for the synthesis of wrightiadione using N,N-diethylcarboxamide as a directed metalation group (DMG) and electrophilic group. The lithiation of N,N-diethylisoflavone-2′-carboxamide with LDA gave a carbanion at C-2 which further cyclized to wrightiadione.Mahidol UniversityChemistryArticleSCOPUS10.1055/s-2003-39313