Chariya KaewsanehaPakorn OpaprakasitDuangporn PolpanichSrung SmanmooPramuan TangboriboonratMahidol UniversitySirindhorn International Institute of Technology, Thammasat UniversityThailand National Science and Technology Development AgencyThailand National Center for Genetic Engineering and Biotechnology2018-09-242018-09-242010-11-01International Journal of Polymer Analysis and Characterization. Vol.15, No.8 (2010), 524-535156353411023666X2-s2.0-78649372958https://repository.li.mahidol.ac.th/handle/20.500.14594/28885Skim latex, a by-product of natural rubber latex, was prevulcanized by sulfur and then used in the preparation of composite particles with disinfectant nanocapsules. Each polymeric nanocapsule contained chlorhexidine digluconate (CHD) as a disinfectant agent encapsulated with poly(methyl acrylate) (PMA) as a shell. The driving force for the heterocoagulation of CHD-PMA nanocapsule and sulfur-prevulcanized skim (SPVS) particle was the electrostatic interaction between the positive charge of lecithin residing on the surface of the nanocapsule and the negative charge from the indigenous surfactant (protein-lipid) and/or from sodium dodecyl sulfate on the surface of the SPVS latex particle. The zeta potential and morphology of heterocoagulated particles indicated the formation of the CHD-PM A/SPVS composite particles. Structures and formation mechanisms of the composite particles with different blend ratios were revealed by depth profiling confocal Raman spectra. © Taylor & Francis Group, LLC.Mahidol UniversityChemical EngineeringChemistryMaterials ScienceArticleSCOPUS10.1080/1023666X.2010.521294