Kamhor A.Tankumpuan T.Wanitkun N.Wongkornrat W.Mahidol University2025-06-082025-06-082025-06-01Nursing Open Vol.12 No.6 (2025)https://repository.li.mahidol.ac.th/handle/123456789/110578Aim: To identify the factors associated with postoperative complications within the first 24 h among individuals who have undergone open-heart surgery. Design: A cross-sectional study. Methods: The participants were 192 elective open-heart surgery patients admitted to a university hospital in Bangkok, Thailand. Data were collected through data recording forms and questionnaires between August 2023 and February 2024, including the clinical frailty scale health questionnaire, serum creatinine assessment form, systemic immune-inflammation index, vasoactive-inotropic score, Society of Thoracic Surgeons risk score and the comprehensive complication index. Multiple regression was used to analyse the data. Results: Most of the participants (64.06%) were male with an average age of 63.14 (13.22) years. Almost a half of them (45.31%) were diagnosed with coronary artery disease. Frailty, kidney function, inflammation, the amount of packed red cells transfused, vasopressors and inotropes and operative risk were statistically significantly the factors affecting the severity of complications in patients after open-heart surgery during the first 24 h. Conclusion: The factors associated with postoperative complications specifically within 24 h after open-heart surgery should be closely monitored, including frailty, kidney function, inflammation, the amount of packed red cells transfused, vasopressors and inotropes and operative risk in order to prevent the postoperative complications. Patient or Public Contribution: All participants contributed to the conducting of this study by participating in a one-day pre-operation and post-operation within 24 h.NursingArticleSCOPUS10.1002/nop2.702412-s2.0-10500709677220541058