Siriporn SaepuaJittra KornsakulkarnPatchanee AuncharoenPranee RachtaweeSurisa KongthongNattawut BoonyuenDavid J. HardingTatsuo NehiraTienthong ThongpanchangChawanee ThongpanchangHiroshima UniversityWalailak UniversityMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2020-03-262020-03-262020-01-01Natural Product Research. (2020)14786427147864192-s2.0-85078025640https://repository.li.mahidol.ac.th/handle/123456789/53537© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Five new compounds, iranginins A–E (1–5), together with sixteen known compounds were isolated from the insect pathogenic fungus Ophiocordyceps irangiensis BCC 2728. The structures and the absolute configurations of the new compounds were established by spectroscopic analyses, the application of modified Mosher’s method (for 2), ECD calculation (for 5), and X-ray crystallographic analysis (for 4). LL-Z1640-5 and mucorisocoumarin C were active against Mycobacterium tuberculosis (MIC 41.7 and 85.0 µM, respectively), while peyroisocoumarin D exhibited cytotoxic activity (IC50 65.6 µM).Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyChemistryArticleSCOPUS10.1080/14786419.2020.1713119