P. PanburanaW. PhuapraditO. PuchaiwatananonMahidol University2018-09-072018-09-072000-01-01Journal of Obstetrics and Gynaecology Research. Vol.26, No.5 (2000), 377-381134180762-s2.0-0033763383https://repository.li.mahidol.ac.th/handle/20.500.14594/26323Objective: To compare the antioxidant nutrients and lipid peroxide levels in preeclampsia and normal pregnant women. Methods: Antioxidant nutrients (vitamin A and E) were measured by high-pressure liquid chromatography, vitamin C was measured by the dinitrophenyl hydrazine method, lipid peroxides were measured by the malondialdehyde method in 20 severe preeclampsia, 30 mild preeclampsia and 60 normal pregnant women as controls. Results: Vitamin C levels in severe and mild preeclampsia were significantly less than those in control group. The corrected vitamin E and vitamin A levels were significantly decreased only in severe preeclampsia. While the lipid peroxide levels in both mild and severe preeclampsia were significantly increased when compared with the normal pregnancy. Conclusions: Preeclampsia is associated with the imbalance between lipid peroxides and antioxidant nutrients (vitamin C and E). The imbalances favour lipid peroxides with the increasing severity of preeclampsia.Mahidol UniversityMedicineArticleSCOPUS10.1111/j.1447-0756.2000.tb01343.x