Massimo SartelliMark A. MalangoniFikri M. Abu-ZidanEwen A. GriffithsStefano Di BellaLynne V. McFarlandIan EltringhamVishal G. ShelatGeorge C. VelmahosCiarán P. KellySahil KhannaZaid M. AbdelsattarLayan AlrahmaniLuca AnsaloniGoran AugustinMiklosh BalaFrédéric BarbutOffir Ben-IshayAneel BhanguWalter L. BifflStephen M. BrecherAdrián Camacho-OrtizMiguel A. CaínzosLaura A. CanterburyFausto CatenaShirley ChanJill R. Cherry-BukowiecJesse ClantonFederico CoccoliniMaria Elena CocuzRaul CoimbraCharles H. CookYunfeng CuiJacek CzepielKoray DasZaza DemetrashviliIsidoro Di CarloSalomone Di SaverioIrina Magdalena DumitruCatherine EckertChristian EckmannEdward H. EilandMushira Abdulaziz EnaniMario FaroPaula FerradaJoseph Derek ForresterGustavo P. FragaJean Louis FrossardRita GaleirasWagih GhnnamCarlos Augusto GomesVenkata GorrepatiMohamed Hassan AhmedTorsten HerzogFelicia HumphreyJae Il KimArda IsikRao IvaturyYeong Yeh LeePaul JuangLuis Furuya-KanamoriAleksandar KaramarkovicPeter K. KimYoram KlugerWen Chien KoFrancis D. LaBarberaJae Gil LeeAri LeppaniemiVarut LohsiriwatSanjay MarwahJohn E. MazuskiGokhan MetanErnest E. MooreFrederick Alan MooreCarl Erik NordCarlos A. OrdoñezGerson Alves Pereira JúniorNicola PetrosilloFrancisco PortelaBasant K. PuriArnab RayMansoor RazaMiran RemsBoris E. SakakushevGabriele SgangaPatrizia SpigagliaDavid B. StewartPierre TattevinJean Francois TimsitKathleen B. ToCristian TranàWaldemar UhlLibor UrbánekHarry van GoorAngela VassalloJean Ralph ZaharEmanuele CaproliPierluigi VialeMacerata HospitalAmerican Board of SurgeryCollege of Medicine and Health Sciences United Arab Emirates UniversityQueen Elizabeth Hospital, University Hospital Birmingham NHS Foundation TrustIRCCS Istituto Nazionale Malattie Infettive Lazzaro SpallanzaniUniversity of Washington, SeattleKing's College Hospital NHS Foundation TrustTan Tock Seng HospitalMassachusetts General HospitalBeth Israel Deaconess Medical CenterMayo ClinicUniversity of Michigan, Ann ArborWayne State UniversityPapa Giovanni XXIII HospitalUniversity of Zagreb School of MedicineHadassah University Medical CentreNational Reference Laboratory for Clostridium difficileDepartment of General SurgeryUniversity of Colorado at DenverVA Medical CenterHospital Universitario Dr. Jose Eleuterio GonzalezUniversidad de Santiago de CompostelaUniversity of AlbertaMaggiore Parma HospitalMedway Maritime HospitalAkron City HospitalUniversitatea Transilvania din BrasovUniversity of California, San Diego, School of MedicineHarvard Medical SchoolTianjin Medical UniversityCollegium Medicum Uniwersytet JagiellonskiegoAdana Numune Training and Research HospitalTbilisi State Medical UniversityHamad General HospitalOspedale MaggioreUniversitatea Ovidius din ConstantaHopital Saint-AntoineHospital of Medical University HannoverVital Care, IncKing Fahad Medical CityFundacao Universitaria do ABC, Faculdade de Medicina do ABCVirginia Commonwealth UniversityStanford UniversityUniversidade Estadual de CampinasHopitaux universitaires de GeneveUniversidade da CoruñaMansoura University, Faculty of MedicineUniversidade Federal de Juiz de ForaPinnacle Health HospitalsNHS Foundation TrustSt. Josef-Hospital im Katholischen Klinikum BochumOchsner Medical Center - New OrleansInje University, College of MedicineErzincan UniversitesiUniversiti Sains Malaysia, Health CampusSt. Louis College of PharmacyAustralian National UniversityUniversity of BelgradeAlbert Einstein College of Medicine of Yeshiva UniversityNational Cheng Kung University HospitalYonsei University College of MedicineHelsinki University HospitalMahidol UniversityPandit Bhagwat Dayal Sharma Postgraduate Institute of Medical SciencesWashington University School of Medicine in St. LouisHacettepe University, Faculty of MedicineUniversity of Florida College of MedicineKarolinska University HospitalUniversidad del Valle, CaliEmergency Surgery and Trauma UnitCentro Hospitalar e Universitario de CoimbraImperial College LondonGeneral Hospital JeseniceMedical University of PlovdivUniversita Cattolica del Sacro Cuore, RomeIstituto Superiore Di SanitaPenn State College of MedicineHopital PontchaillouHopital Bichat-Claude-Bernard AP-HPFakultni Nemocnice BrnoRadboud University Nijmegen Medical CentreSaint John's Health CenterUniversite d'AngersAzienda Ospedaliera Universitaria Ospedali Riuniti, AnconaAlma Mater Studiorum Universita di Bologna2018-11-232018-11-232015-08-20World Journal of Emergency Surgery. Vol.10, No.1 (2015)174979222-s2.0-84939477059https://repository.li.mahidol.ac.th/handle/20.500.14594/36347© 2015 Sartelli et al. In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.Mahidol UniversityMedicineArticleSCOPUS10.1186/s13017-015-0033-6