Palladium-mediated heck-type reactions of [(Bromodifluoromethyl)sulfonyl] benzene: Synthesis of α-alkenyl- and α-heteroaryl-substituted α,α-difluoromethyl phenyl sulfones

Nakin SurapanichChutima KuhakarnManat PohmakotrVichai ReutrakulMahidol University2018-06-112018-06-112012-10-01European Journal of Organic Chemistry. No.30 (2012), 5943-5952109906901434193X2-s2.0-84867616227https://repository.li.mahidol.ac.th/handle/123456789/13941Palladium-catalyzed Heck-type reactions of [(bromodifluoromethyl)sulfonyl] benzene (1) with styrene derivatives and heteroaromatic compounds successfully gave α-alkenyl- and α-heteroaryl-substituted α,α- difluoromethyl phenyl sulfones, respectively. Palladium-catalyzed Heck-type reactions of [(bromodifluoromethyl)sulfonyl] benzene (1) are reported. Both styrene derivatives and heteroaromatic compounds gave PhSO 2 CF 2 -substituted products in moderate to good yields. © 2012 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.Mahidol UniversityChemistryPalladium-mediated heck-type reactions of [(Bromodifluoromethyl)sulfonyl] benzene: Synthesis of α-alkenyl- and α-heteroaryl-substituted α,α-difluoromethyl phenyl sulfonesArticleSCOPUS10.1002/ejoc.201200613