La-ongthong K.Chantarojsiri T.Soorukram D.Leowanawat P.Reutrakul V.Kuhakarn C.Mahidol University2024-04-182024-04-182024-01-01Chemistry - An Asian Journal (2024)18614728https://repository.li.mahidol.ac.th/handle/123456789/98024A benign electrochemical method to access 6-methylphenanthridines from 2-isocyanobiaryls using N,N-dimethylformamide (DMF) as a methyl source is reported. The protocol operates at ambient temperature without the need for harmful methylating reagents. Mechanistic studies suggested that DMF delivered a methylene synthon, followed by reduction at the cathode and tautomerization. The method offers environmental benefits by avoiding metal-based reagents and harsh conditions.ChemistryBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1002/asia.2024001762-s2.0-851899709951861471X