N. NasongklaP. AkarajiratunS. HongengMahidol University2018-09-132018-09-132009-12-01IFMBE Proceedings. Vol.25, No.8 (2009), 317-320168007372-s2.0-77949877644https://repository.li.mahidol.ac.th/handle/123456789/27369Tri-component copolymers of poly(ε-caprolactone)- random-poly(D,L- lactide)-block-poly(ethylene glycol)-blockpoly( ε-caprolactone)-random- poly(D,L-lactide) (PLCA-PEGPLCA or PLEC) were used as a material to develop cylindrical polymeric rods and were used as the implantable drug delivery system. PLEC was successfully synthesized and the copolymer ratio and molecular weight were controllable. Trypan blue was selected as a model drug and the release profiles of trypan blue were carried out at 20 and 30 % loading. The release rate of trypan blue was found to directly depend on the amount of lactide in PLEC and the amount of trypan blue. © 2009 Springer-Verlag.Mahidol UniversityChemical EngineeringEngineeringConference PaperSCOPUS10.1007/978-3-642-03887-7-92