Insti InstiatyNiklas LindegardhPodjanee JittmalWarunee HanpithakpongDaniel BlessbornSasithon PukrittayakameeNicholas J. WhiteJoel TarningMahidol UniversityNuffield Department of Clinical Medicine2018-10-192018-10-192013-06-01Antimicrobial Agents and Chemotherapy. Vol.57, No.6 (2013), 2858-286210986596006648042-s2.0-84877867722https://repository.li.mahidol.ac.th/handle/20.500.14594/32320Oseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers. Median (range) venous-blood-to-plasma ratios were 1.42 (0.920 to 1.97) for oseltamivir and 0.673 (0.564 to 0.814) for oseltamivir carboxylate. Capillary blood/venous plasma ratios were 1.32 (0.737 to 3.16) for oseltamivir and 0.685 (0.502 to 1.34) for oseltamivir carboxylate. Oseltamivir concentrations in venous and capillary blood were similar. Oseltamivir carboxylate showed a time-dependent distribution between venous and capillary blood. Copyright © 2013, American Society for Microbiology. All Rights Reserved.Mahidol UniversityMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1128/AAC.02408-12