Arjen M. DondorpPiet A. KagerJohan VreekenNicholas J. WhiteAcademic Medical Centre, University of AmsterdamMahidol University2018-09-072018-09-072000-06-01Parasitology Today. Vol.16, No.6 (2000), 228-232016947582-s2.0-0034212451https://repository.li.mahidol.ac.th/handle/20.500.14594/25983Obstruction of the microcirculation plays a central role in the pathophysiology of severe malaria. Here, Arjen Dondorp and colleagues describe the various contributors to impaired microcirculatory flow in falciparum malaria: sequestration, rosetting and recent findings regarding impaired red blood cell deformability. The correlation with clinical findings and possible therapeutic consequences are discussed.Mahidol UniversityImmunology and MicrobiologyReviewSCOPUS10.1016/S0169-4758(00)01666-5