Quah P.L.Buist A.S Chandra P.Chen H.Chua T.E.Hui P.w.Shah M.Surjaningrum E.R.Muniswaran G.Mettananda S.Boriboonhirunsarn D.Tan K.H.Mahidol University2025-10-202025-10-202025-11-01Asian Journal of Psychiatry Vol.113 (2025)18762018https://repository.li.mahidol.ac.th/handle/123456789/112661Background: The perinatal period, from conception to one year postpartum, is a time of major physical and emotional change, with heightened risk for mental health disorders such as anxiety and depression—particularly in the Asia-Pacific region. Poor maternal mental health during this phase can lead to obstetric complications and adversely affect child development and neurodevelopment. Method: Representatives from 11 Asia–Pacific nations and/or jurisdictions developed a consensus statement on the perinatal mental health guidelines on depression and anxiety using the GRADE-ADOLOPMENT framework. Findings: These guidelines support all women of childbearing age, including those with special circumstances—such as severe obstetric complications, adolescent pregnancies, or special needs—and their infants. Recommendations included special considerations for women who experienced severe maternal complications, personalized care for adolescents and women with unique needs, and attention to the mental health needs of infants. They focus on promoting optimal mental health for women experiencing depression and anxiety during the preconception, antenatal, and postnatal periods. Interpretation: These guidelines, developed for maternal and child health practitioners in the Asia-Pacific, promote a holistic approach—combining lifestyle changes, early screening, and tailored interventions—to improve perinatal mental health and enhance outcomes for mothers and children.PsychologyMedicineReviewSCOPUS10.1016/j.ajp.2025.1047202-s2.0-10501859652018762026