Poonsakdi PloypradithWiyada JinagluengChitkavee PavaroSomsak RuchirawatChulabhorn Research InstituteMahidol University2018-07-242018-07-242003-02-10Tetrahedron Letters. Vol.44, No.7 (2003), 1363-1366004040392-s2.0-0037429073https://repository.li.mahidol.ac.th/handle/20.500.14594/20762Direct metal-halogen exchange of 2-bromopyrrole carbonate derivatives with tert-butyllithium followed by the intramolecular lactonization of the resulting 2-pyrrole anion onto the carbonate provided the corresponding lamellarins in moderate to good yield. The lamellarin framework could be obtained from the direct metal-halogen exchange strategy in a 26-33% overall yield over 5-6 steps. © 2003 Elsevier Science Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/S0040-4039(02)02887-3