Adisak ChatupheeraphatDarunee SoorukramChutima KuhakarnPatoomratana TuchindaVichai ReutrakulChaveng PakawatchaiSaowanit SaithongManat PohmakotrMahidol UniversityPrince of Songkla University2018-10-192018-10-192013-10-01European Journal of Organic Chemistry. No.30 (2013), 6844-6858109906901434193X2-s2.0-84885597753https://repository.li.mahidol.ac.th/handle/20.500.14594/31510PhSCF2TMS was utilized as a useful gem-difluoromethylene building block for the synthesis of gem-difluoromethylenated spiro-γ-butyrolactones. The radical cyclization of γ-alkenyl- γ-gem-difluoro(phenylsulfanyl)methyl-γ-butyrolactones provided gem-difluoromethylenated spiro-γ-butyrolactones. PhSCF2TMS (TMS = trimethylsilyl) is utilized as a gem-difluoromethylenating agent for the synthesis of gem-difluoromethylenated spiro-γ-butyrolactones. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Mahidol UniversityChemistryArticleSCOPUS10.1002/ejoc.201300998