Wilawan MahabusarakamKunnika KuahaPrapon WilairatWalter C. TaylorPrince of Songkla UniversityKhon Kaen UniversityMahidol UniversityThe University of Sydney2018-08-202018-08-202006-08-01Planta Medica. Vol.72, No.10 (2006), 912-916003209432-s2.0-33748592259https://repository.li.mahidol.ac.th/handle/123456789/23002Mangostin, the major xanthone of Garcinia mangostana, and a series of synthetic derivatives were investigated for their in vitro antiplasmodial activity against Plasmodium falciparum. Mangostin itself showed moderate activity, but prenylated xanthones containing alkylamino functional groups exhibited quite potent antiplasmodial activity. Some structure-activity relationships are proposed. © Georg Thieme Verlag KG Stuttgart.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1055/s-2006-947190