Warunee NgrenngarmlertChutipong SukkanonRapeeporn YaicharoenTheeraphap ChareonviriyaphapMahidol UniversityKasetsart University2018-12-112019-03-142018-12-112019-03-142016-10-01Acta Tropica. Vol.162, (2016), 239-244187362540001706X2-s2.0-84979255387https://repository.li.mahidol.ac.th/handle/123456789/40703© 2016 Although silicone-based monomolecular film (MMF) has been accepted as larvicide in several countries, its mosquito control potential has never been investigated in Thailand. Laboratory assessment in this study was conducted to determine the MMF efficacy against Aedes aegypti. At the recommended dosage (1 mL/m2of water surface), mortality of pupae (99.17 ± 0.83%) was significantly greater than mortality of old and young larvae (73.33 ± 9.13, 11.67 ± 3.47%; respectively). Pupicidal activity was rapidly exhibited within hours while larvicidal activity took at least one day. Interestingly, among the survived mosquitoes after MMF exposure, larval length (3.6 ± 0.18 mm), pupation (0%) and adult emergence (0%) were significantly less than the control group. Gravid females also avoided laying eggs in MMF-treated oviposition cups. There was no influence of physical factors on MMF efficacy and no toxic effects on fish and plants. These results indicated the MMF is promising to provide not only larvicidal and pupicidal activity but also inhibition of larval development as indicated by both larval length and stage transformation.Mahidol UniversityImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/j.actatropica.2016.07.012