Dong Dong LuoKai PengJia Yu YangPawinee PiyachaturawatWitchuda SaengsawangLei AoWan Zhou ZhaoYu TangSheng Biao WanOcean University of ChinaMahidol UniversityNanjing OGpharma Co. Ltd.2019-08-232019-08-232018-01-01RSC Advances. Vol.8, No.52 (2018), 29548-29554204620692-s2.0-85052630066https://repository.li.mahidol.ac.th/handle/20.500.14594/45454© 2018 The Royal Society of Chemistry. A simple and efficient protocol was developed for the syntheses of oridonin analogues, i.e. 6,20-epoxy ent-kaurane diterpenoid analogues from oridonin via diethylaminosulfur trifluoride (DAST) promoted rearrangement, most of which exhibited superior anticancer activities compared with their precursor.Mahidol UniversityChemical EngineeringChemistryStructural modification of oridonin: Via DAST induced rearrangementArticleSCOPUS10.1039/c8ra05728a