Songsak PetmitrPrapon WilairatJiraporn KownkonPranee WinichagoonSuthat FucharoenMahidol UniversityFaculty of Medicine, Thammasat University2018-06-142018-06-141989-07-31Biochemical and Biophysical Research Communications. Vol.162, No.2 (1989), 846-851109021040006291X2-s2.0-0024315888https://repository.li.mahidol.ac.th/handle/123456789/15707The molecular basis of β o -thalassemia/HbE disease in 30 Thai patients was investigated using DNA amplification and dot-blot hybridization with a number of allele specific oligonucleotide probes. The mutations identified were 17 cases of 4 base-pair deletion at codons 41-42, 4 cases of amber mutation at codon 17, and one case each of an ochre mutation at codon 35, a single base substitution at position 5 of IVS-1, and a single base substitution at position 654 of IVS-2. © 1989.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/0006-291X(89)92387-5