C. SadavongvivadJ. SatayavivadV. PrachayasittikulL. Mo-SuwunMahidol University2018-06-012018-06-011978-12-01General Pharmacology: Vascular System. Vol.8, No.4 (1978), 263-267030636232-s2.0-0018116878https://repository.li.mahidol.ac.th/handle/123456789/13134Lowering temperature r420w9 =and the reduced maximal effects of all four common adrenoceptor agonists without any change in their potencies. Quinidine reduced their potencies slightly and lowered maximal effects only at high concentrations. Adenosine caused a large decrease in potency of isoprenaline but hardly affected that of phenylephrine. These andthe authors previous results indicate that some endogeneous negative chronotropic agents can alter relative potencies of the agonists as well as characteristics of blockers.Mahidol UniversityPharmacology, Toxicology and PharmaceuticsModification of relative potencies of beta-adrenoceptor agonists by negative chronotropic agents in rat atriumArticleSCOPUS