Renée M. NedJulie M. MooreSujittra ChaisavaneeyakornVenkatachalam UdhayakumarNational Center for Infectious DiseasesThe University of GeorgiaAtlanta Research and Education FoundationMahidol University2018-06-212018-06-212005-06-01Trends in Parasitology. Vol.21, No.6 (2005), 284-291147149222-s2.0-19444371421https://repository.li.mahidol.ac.th/handle/20.500.14594/16586Infection with either HIV or malaria during pregnancy often results in adverse outcomes for mother and child. Co-infection further increases the risks of these events, which include maternal anemia and babies with low birth weight. The immunological bases for the increased susceptibility of HIV-infected mothers to malaria and for the effect of co-infection on mother-to-child transmission of HIV are areas of major importance in public health. In this article, we review current data about humoral and cellular responses to HIV-placental-malaria co-infection and present an immunological hypothesis to explain the epidemiological findings.Mahidol UniversityImmunology and MicrobiologyMedicineReviewSCOPUS10.1016/j.pt.2005.04.010