Damrongkiet ArthanJisnuson SvastiPrasat KittakoopDaraporn PittayakhachonwutMorakot TanticharoenYodhathai ThebtaranonthMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2018-07-242018-07-242002-02-26Phytochemistry. Vol.59, No.4 (2002), 459-463003194222-s2.0-0037176744https://repository.li.mahidol.ac.th/handle/123456789/19991The C-4 sulfated isoflavonoid, torvanol A (1), and the steroidal glycoside, torvoside H (3), together with the known glycoside, torvoside A (2), were isolated from a MeOH extract of Solanum torvum fruits. Upon enzymatic hydrolysis with β-glucosidase, torvoside A (2) and torvoside H (3) yielded the corresponding acetal derivatives 4 and 5, respectively. Torvanol A (1), torvoside H (3) and compound 5 exhibited antiviral activity (herpes simplex virus type 1) with IC50values of 9.6, 23.2 and 17.4 μg/ml, respectively. Compounds 1-5 showed no cytotoxicity (at 50 μg/ml) against BC, KB and Vero cell lines. © 2002 Elsevier Science Ltd. All rights reserved.Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/S0031-9422(01)00417-4