Aftab A. AnsariAnn E. MayneNattawat OnlamoonKovit PattanapanyasatKazuyasu MoriFrancois VillingerEmory UniversityMahidol UniversityTropical Agriculture Research Center2018-07-242018-07-242004-07-07Immunologic Research. Vol.29, No.1-3 (2004), 1-170257277X2-s2.0-3042658737https://repository.li.mahidol.ac.th/handle/20.500.14594/21369Outbreaks of infectious diseases such as HIV and the much televised and attention-getting outbreaks of diseases such as Ebola, Hantaviruses, and the most recent outbreak of SARS have induced a significant new interest in the formulations and more importantly the science of vaccinology, which has previously to a large extent been conducted empirically. Our laboratory has focused on the use of recombinant nonhuman primate cytokines as adjunctive therapies for inducing antigen-specific immune responses in monkeys because most recombinant human cytokines appear to be immunogenic. This article provides a summary of our work with such cytokines, which includes attempts to define optimum dosing schedules that lead to optimal primary and lasting memory antigen-specific immune responses.Mahidol UniversityImmunology and MicrobiologyReviewSCOPUS