Ubonwan PongprayoonTuanta SematongPatoomratana TuchindaPer ClaesonVichai ReutrakulNilufar NaharThailand Ministry of Science and TechnologyMahidol UniversityUniversity of Dhaka2018-07-042018-07-041996-01-01Phytotherapy Research. Vol.10, No.6 (1996), 534-5350951418X2-s2.0-0029803473https://repository.li.mahidol.ac.th/handle/123456789/17588Two diterpenes, 2α-acetoxysandraracopimaradien-1α-ol (1) and sandaracopimaradien-1α,2α-diol (2) isolated from Kaempferia pulchra Ridl. (Zingiberaceae), have been assayed for topical antiinflammatory activity in the model of 12-O-tetradecanoylphorbol-13-acetate-induced ear oedema in rats. Both substances were found active and the ID50-values were estimated to be 330 and 50 μg/ear, respectively. The ID50-value of the reference drug diclofenac was calculated to 90 μg/ear.Mahidol UniversityChemistryPharmacology, Toxicology and PharmaceuticsTopical antiinflammatory activity of two pimarane diterpenes from Kaempferia pulchraArticleSCOPUS10.1002/(SICI)1099-1573(199609)10:6<534::AID-PTR890>3.0.CO;2-C