Genetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries

Naowarat TanomsingMayfong MayxayPaul N. NewtonFrancois NostenChristiane DolecekTran Tinh HienNicholas J. WhiteNicholas P.J. DayArjen M. DondorpMallika ImwongMahidol UniversityMahosot HospitalUniversity of Health SciencesNuffield Department of Clinical MedicineUCL2018-11-092018-11-092014-04-03PLoS ONE. Vol.9, No.4 (2014)193262032-s2.0-84899412014https://repository.li.mahidol.ac.th/handle/20.500.14594/33028The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance. © 2014 Tanomsing et al.Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyGenetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countriesArticleSCOPUS10.1371/journal.pone.0093942