Kornkamon CheawthamaiMantana VongsirinavaratVimonwan HiengkaewSasithorn SaengrueangrobMahidol University. Faculty of Physical Therapy2018-04-232018-04-232018-042014Journal of the medical association of Thailand. Vol.97, No.7 (2014), S95-S100https://repository.li.mahidol.ac.th/handle/20.500.14594/10937Objective: The present study aimed to compare the effectiveness of the treatment programs of home-based exercise with and without self-manual therapy in individuals with knee osteoarthritis (knee OA) in community. Material and Method: Forty-three participants with knee OA were randomly assigned in groups. All participants received the same home-based exercise program with or without self-manual therapy over 12 weeks. Outcome measures were pain intensity, range of motions, six-minute walk test distance, the knee injury and osteoarthritis outcome score (KOOS), shortform 36 (SF-36) and satisfaction. Results: The results showed that the self-manual therapy program significantly decreased pain at 4 weeks, increased flexion and extension at 4 and 12 weeks, and improved the KOOS in pain item and SF-36 in physical function and mental health items. The home-based exercise group showed significant increase of the six-minute walk distance at 4 and 12 weeks, improvements in the KOOS in pain and symptom items and SF-36 in the physical function and role-emotional items. Conclusion: Overall, the results favored a combination of self-manual therapy and home-based exercise for patients with knee OA, which apparently showed superior benefits in decreasing pain and improving active knee range of motions.engMahidol UniversityKnee osteoarthritisSelf-manual therapyHome-based exercisePhysical therapyCommunityArticleThe Medical Association of Thailand